QUERCETIN

Quercetin is one of a broad group of natural polyphenolic flavonoid substances (plant pigment) that are being investigated for their widespread health benefits. These benefits have generally been ascribed to its combination of antioxidant and anti-inflammatory activity. Recent in vitro evidence suggests that improved mitochondrial biogenesis could play an important role to the fitness without exercise training.

Foods rich in quercetin include black and green tea, apples, red onions , red grapes, tomato and broccoli. In the amounts consumed in a healthy diet, quercetin "is unlikely to cause any major problems or benefits but also but the U.S. Food and Drug Administration has not approved any health claims for quercetin.

Although many studies have been propose an anticancer activity for quercetin in vitro controlled clinical trials are needed to show whether quercetin has helpful properties in humans. Please note that prenatal exposure to flavonoids associated with increase in the incidence of malignancies in DNA repair-deficient mice.

Boly R, Gras T, Lamkami T, Guissou P, Serteyn D, Kiss R, Dubois J. Quercetin inhibits a large panel of kinases implicated in cancer cell biology. Int J Oncol. 2011 Mar;38(3):833-42.

Vanhees K, de Bock L, Godschalk RW, van Schooten FJ, van Waalwijk van Doorn-Khosrovani SB.

Prenatal exposure to flavonoids: implication for cancer risk. Toxicol Sci. 2010 Dec 21.

Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7. Davis JM, Murphy EA, Carmichael MD, Davis B.

Quercetin increases brain and muscle mitochondrial biogenesis and exercise tolerance. Am J Physiol Regul Integr Comp Physiol. 2009 Apr;296(4):R1071-7

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